Preparing the hair follicle canal for hair shaft emergence
نویسندگان
چکیده
منابع مشابه
BMPR1A signaling is necessary for hair follicle cycling and hair shaft differentiation in mice.
Interactions between ectodermal and mesenchymal extracellular signaling pathways regulate hair follicle (HF) morphogenesis and hair cycling. Bone morphogenetic proteins (BMPs) are known to be important in hair follicle development by affecting the local cell fate modulation. To study the role of BMP signaling in the HF, we disrupted Bmpr1a, which encodes the BMP receptor type IA (BMPR1A) in an ...
متن کاملLocalization of Hair Shaft Protein VSIG8 in the Hair Follicle, Nail Unit, and Oral Cavity
TO THE EDITOR The molecular bases of diseases of the epidermal appendages are gradually being elucidated as genes encoding their constituents and regulation are being defined. A direct correspondence between altered protein sequence and aberrant hair shaft structure is evident in cases such as monilethrix (Schweizer, 2006). In others, gene defects lead to altered development and thus perturbed ...
متن کاملMiz1 is required for hair follicle structure and hair morphogenesis.
Previous work has implicated the Myc-binding transcription factor Miz1 in the control of keratinocyte proliferation and in the cellular response to TGFbeta. Miz1 is expressed in basal keratinocytes of the interfollicular epidermis and in hair follicles. Here we have conditionally knocked out the POZ/BTB transactivation domain of Miz1 in keratinocytes using a keratin 14 (K14)-Cre mouse deleter s...
متن کاملHair follicle nevus.
We present a case of hair follicle nevus, a rare hamartoma composed of vellus hair follicles. Hair follicle nevus should be differentiated from accessory auricle, trichofolliculoma and hair nevus.
متن کاملLocalization of the Novel Hair Shaft Protein VSIG8 in the Hair Follicle, Nail Unit and Oral Cavity
The molecular bases of diseases of the epidermal appendages are gradually being elucidated as genes encoding their constituents and regulation are defined. A direct correspondence between altered protein sequence and aberrant hair shaft structure is evident in cases such as monilethrix (Schweizer, 2006). In others, gene defects lead to altered development and thus perturbed regulation of compon...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2020
ISSN: 0906-6705,1600-0625
DOI: 10.1111/exd.14210